usaid-gov/a-genomewide-association-and-metaanalysis-common-dffz-hp35
Icon for Socrata external plugin
Open repository in Console
 
Readme
Updated 1 year ago
Indexed 1 month ago

A genome‑wide association and meta‑analysis: Common bean syntelogs and their corresponding cowpea genes

Seed size is an important trait for yield and commercial value in dry-grain cowpea. Seed size varies widely among different cowpea accessions, and the genetic basis of such variation is not yet well understood. To better decipher the genetic basis of seed size, a genome-wide association study (GWAS) and meta-analysis were conducted on a panel of 368 cowpea diverse accessions from 51 countries. Four traits, including seed weight, length, width and density were evaluated across three locations. Using 51,128 single nucleotide polymorphisms covering the cowpea genome, 17 loci were identified for these traits. One locus was common to weight, width and length, suggesting pleiotropy. By integrating synteny-based analysis with common bean, six candidate genes (Vigun05g036000, Vigun05g039600, Vigun05g204200, Vigun08g217000, Vigun11g187000, and Vigun11g191300) which are implicated in multiple functional categories related to seed size such as endosperm development, embryo development, and cell elongation were identified. These results suggest that a combination of GWAS meta-analysis with synteny comparison in a related plant is an efficient approach to identify candidate gene (s) for complex traits in cowpea. The identified loci and candidate genes provide useful information for improving cowpea varieties and for molecular investigation of seed size.

Querying over HTTP

Splitgraph serves as an HTTP API that lets you run SQL queries directly on this data to power Web applications. For example:

curl https://data.splitgraph.com/sql/query/ddn \
    -H "Content-Type: application/json" \
    -d@-<<EOF
{"sql": "
    SELECT *
    FROM \"usaid-gov/a-genomewide-association-and-metaanalysis-common-dffz-hp35\".\"a_genomewide_association_and_metaanalysis_common\"
    LIMIT 100 
"}
EOF

See the Splitgraph documentation for more information.

 
Preview
  • a_genomewide_association_and_metaanalysis_common
     
     
     
     
     
Upstream Metadata